Rodatin
Categoria
Rodatin Marchi, Rodatin Analoghi
- 6 alpha-Methylcompactin
- Altocor
- Altoprev
- Artein
- Belvas
- Cholestra
- Closterol
- Colevix
- Compactin
- Hipolip
- Hipovastin
- Lestatin
- Lipdip
- Lipivas
- Lipofren
- Lovalip
- Lovalord
- Lovastatin [Usan:Ban:Inn]
- Lovastatina [Spanish]
- Lovastatine [French]
- Lovastatinum [Latin]
- Lovasterol
- Lovastin
- Lozutin
- Mevacor
- Mevastatin
- Mevinacor
- Mevinolin
- Mevlor
- Monacolin K
- Nergadan
- Paschol
- Pravastatin
- Rodatin
- Rovacor
- Sivlor
- Taucor
- Tecnolip
- Teroltrat
Rodatin Marchi miscela
Rodatin Formula chimica
C24H36O5
Rodatin RX link
http://www.rxlist.com/cgi/generic3/altocor.htm
Rodatin FDA foglio
Rodatin DMS (foglio di materiale di sicurezza)
Rodatin Sintesi di riferimento
Monaghan RL et al. US Pat. 4,231,938 (1980)
Rodatin Peso molecolare
404.54 g/mol
Rodatin Temperatura di fusione
174.5 oC
Rodatin H2O Solubilita
0,0004 mg / mL
Rodatin Stato
Solid
Rodatin LogP
4
Rodatin Forme di dosaggio
Compressa
Rodatin Indicazione
Per la gestione in aggiunta alla dieta per ridurre le elevate totale-C, C-LDL, Apo B, TG e livelli in pazienti con ipercolesterolemia primaria e dislipidemia mista, per la prevenzione primaria della malattia coronarica
Rodatin Farmacologia
Lovastatina, un agente antilipemic prodotto dalla fermentazione di Aspergillus terreus, è il primo di una classe di farmaci ipolipemizzanti conosciuta come inibitori dell'HMG-CoA reduttasi. Lovastatina è usato per trattare ipercolesterolemia, per rallentare l'aterosclerosi coronarica, e per prevenire infarto miocardico e ictus. Lovastatina, come simvastin ea differenza di pravastatina, è un profarmaco, concentrandosi farmaco attivo nel fegato durante il primo passaggio circolazione.
Rodatin Assorbimento
30%
Rodatin Tossicita
LD50> 1000 mg / kg (per via orale nei topi)
Rodatin Informazioni paziente
PATIENT INFORMATION
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Rodatin Atto interessato organismi
Gli esseri umani e altri mammiferi
