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Mevlor Brand names, Mevlor Analogs

Mevlor Brand Names Mixture

  • No information avaliable

Mevlor Chemical_Formula


Mevlor RX_link

Mevlor fda sheet

Mevlor FDA

Mevlor msds (material safety sheet)

Mevlor Synthesis Reference

R. L. Monaghan et al., U.S. Pat. 4,231,938 (1980)

Mevlor Molecular Weight

404.54 g/mol

Mevlor Melting Point

174.5 oC

Mevlor H2O Solubility

0.0004 mg/mL

Mevlor State


Mevlor LogP


Mevlor Dosage Forms


Mevlor Indication

For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia; For primary prevention of coronary heart disease

Mevlor Pharmacology

Lovastatin, an antilipemic agent produced by fermentation of Aspergillus terreus, is the first of a class of lipid-lowering agents known as the HMG-CoA reductase inhibitors. Lovastatin is used to treat hypercholesterolemia, to slow coronary atherosclerosis, and to prevent myocardial infarction and stroke. Lovastatin, like simvastin and unlike pravastatin, is a prodrug, concentrating active drug in the liver during first-pass circulation.

Mevlor Absorption


Mevlor side effects and Toxicity

LD50>1000 mg/kg (orally in mice)

Mevlor Patient Information


Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.

Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .

Mevlor Organisms Affected

Humans and other mammals