Monacolin K
Categoria
Monacolin K Marchi, Monacolin K Analoghi
- 6 alpha-Methylcompactin
- Altocor
- Altoprev
- Artein
- Belvas
- Cholestra
- Closterol
- Colevix
- Compactin
- Hipolip
- Hipovastin
- Lestatin
- Lipdip
- Lipivas
- Lipofren
- Lovalip
- Lovalord
- Lovastatin [Usan:Ban:Inn]
- Lovastatina [Spanish]
- Lovastatine [French]
- Lovastatinum [Latin]
- Lovasterol
- Lovastin
- Lozutin
- Mevacor
- Mevastatin
- Mevinacor
- Mevinolin
- Mevlor
- Monacolin K
- Nergadan
- Paschol
- Pravastatin
- Rodatin
- Rovacor
- Sivlor
- Taucor
- Tecnolip
- Teroltrat
Monacolin K Marchi miscela
Monacolin K Formula chimica
C24H36O5
Monacolin K RX link
http://www.rxlist.com/cgi/generic3/altocor.htm
Monacolin K FDA foglio
Monacolin K DMS (foglio di materiale di sicurezza)
Monacolin K Sintesi di riferimento
Monaghan RL et al. US Pat. 4,231,938 (1980)
Monacolin K Peso molecolare
404.54 g/mol
Monacolin K Temperatura di fusione
174.5 oC
Monacolin K H2O Solubilita
0,0004 mg / mL
Monacolin K Stato
Solid
Monacolin K LogP
4
Monacolin K Forme di dosaggio
Compressa
Monacolin K Indicazione
Per la gestione in aggiunta alla dieta per ridurre le elevate totale-C, C-LDL, Apo B, TG e livelli in pazienti con ipercolesterolemia primaria e dislipidemia mista, per la prevenzione primaria della malattia coronarica
Monacolin K Farmacologia
Lovastatina, un agente antilipemic prodotto dalla fermentazione di Aspergillus terreus, è il primo di una classe di farmaci ipolipemizzanti conosciuta come inibitori dell'HMG-CoA reduttasi. Lovastatina è usato per trattare ipercolesterolemia, per rallentare l'aterosclerosi coronarica, e per prevenire infarto miocardico e ictus. Lovastatina, come simvastin ea differenza di pravastatina, è un profarmaco, concentrandosi farmaco attivo nel fegato durante il primo passaggio circolazione.
Monacolin K Assorbimento
30%
Monacolin K Tossicita
LD50> 1000 mg / kg (per via orale nei topi)
Monacolin K Informazioni paziente
PATIENT INFORMATION
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Monacolin K Atto interessato organismi
Gli esseri umani e altri mammiferi
