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Lopresor
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Analoghi
Lopresor
Marchi miscela
LOPRESSOR HCT
Lopresor
Formula chimica
C15H25NO3
Lopresor
RX link
http://www.rxlist.com/cgi/generic/metopxl.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
Brandstorm AE et al. US Pat. 3,873,600 (1975)
Lopresor
Peso molecolare
267.364 g/mol
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Temperatura di fusione
120 oC (tartarate salt)
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H2O Solubilita
16,9 mg / ml
Lopresor
Stato
Solid
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LogP
2.477
Lopresor
Forme di dosaggio
Compressa
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Indicazione
Per il trattamento di ipertensione e angina pectoris.
Lopresor
Farmacologia
Metoprololo, un antagonista competitivo adrenergico beta1-selettivo (cardioselettivi), è simile a atenololo nella sua liposolubilità moderata, la mancanza di attività simpaticomimetica intrinseca (ISA), e la membrana debole attività stabilizzante (MSA).
Lopresor
Assorbimento
Rapida e completa, il 50%
Lopresor
Tossicita
LD50 = 5500 mg / kg (per via orale nei ratti), effetti tossici includono bradicardia, ipotensione, broncospasmo e insufficienza cardiaca. LD50 = 2090 mg / kg (per via orale nei topi)
Lopresor
Informazioni paziente
Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This
medication can also be used to treat a heart condition called angina. This particular formulation is an extended
release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or
right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This
medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this
medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble
breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is
important to inform all your healthcare providers that you are taking this medication, especially before any
surgeries or procedures.
Lopresor
Atto interessato organismi
Gli esseri umani e altri mammiferi