Metoprolol Tartrate

Metoprolol Tartrate Brand names, Metoprolol Tartrate Analogs

Metoprolol Tartrate Brand Names Mixture

LOPRESSOR HCT

Metoprolol Tartrate Chemical_Formula

C₁₅H₂₅NO₃

Metoprolol Tartrate RX_link

http://www.rxlist.com/cgi/generic/metopxl.htm

Metoprolol Tartrate fda sheet

Metoprolol_Tartrate FDA

Metoprolol Tartrate msds (material safety sheet)

Metoprolol_Tartrate MSDS

Metoprolol Tartrate Synthesis Reference

A. E. Brandstorm et al., U.S. Pat. 3,873,600 (1975)

Metoprolol Tartrate Molecular Weight

267.364 g/mol

Metoprolol Tartrate Melting Point

120 ^oC (tartarate salt)

Metoprolol Tartrate H₂O Solubility

16.9 mg/mL

Metoprolol Tartrate State

Solid

Metoprolol Tartrate LogP

2.477

Metoprolol Tartrate Dosage Forms

Tablet

Metoprolol Tartrate Indication

For the treatment of hypertension and angina pectoris.

Metoprolol Tartrate Pharmacology

Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).

Metoprolol Tartrate Absorption

Rapid and complete, 50%

Metoprolol Tartrate side effects and Toxicity

LD₅₀=5500 mg/kg (orally in rats), toxic effects include bradycardia, hypotension, bronchospasm, and cardiac failure. LD₅₀=2090 mg/kg (orally in mice)

Metoprolol Tartrate Patient Information

Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This medication can also be used to treat a heart condition called angina. This particular formulation is an extended release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is important to inform all your healthcare providers that you are taking this medication, especially before any surgeries or procedures.

Metoprolol Tartrate Organisms Affected

Humans and other mammals