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Toprol-XL Brand names, Toprol-XL Analogs

Toprol-XL Brand Names Mixture


Toprol-XL Chemical_Formula


Toprol-XL RX_link

Toprol-XL fda sheet

Toprol-XL FDA

Toprol-XL msds (material safety sheet)

Toprol-XL MSDS

Toprol-XL Synthesis Reference

A. E. Brandstorm et al., U.S. Pat. 3,873,600 (1975)

Toprol-XL Molecular Weight

267.364 g/mol

Toprol-XL Melting Point

120 oC (tartarate salt)

Toprol-XL H2O Solubility

16.9 mg/mL

Toprol-XL State


Toprol-XL LogP


Toprol-XL Dosage Forms


Toprol-XL Indication

For the treatment of hypertension and angina pectoris.

Toprol-XL Pharmacology

Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).

Toprol-XL Absorption

Rapid and complete, 50%

Toprol-XL side effects and Toxicity

LD50=5500 mg/kg (orally in rats), toxic effects include bradycardia, hypotension, bronchospasm, and cardiac failure. LD50=2090 mg/kg (orally in mice)

Toprol-XL Patient Information

Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This medication can also be used to treat a heart condition called angina. This particular formulation is an extended release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is important to inform all your healthcare providers that you are taking this medication, especially before any surgeries or procedures.

Toprol-XL Organisms Affected

Humans and other mammals