Seloken

Seloken Brand names, Seloken Analogs

Seloken Brand Names Mixture

LOPRESSOR HCT

Seloken Chemical_Formula

C₁₅H₂₅NO₃

Seloken RX_link

http://www.rxlist.com/cgi/generic/metopxl.htm

Seloken fda sheet

Seloken FDA

Seloken msds (material safety sheet)

Seloken MSDS

Seloken Synthesis Reference

A. E. Brandstorm et al., U.S. Pat. 3,873,600 (1975)

Seloken Molecular Weight

267.364 g/mol

Seloken Melting Point

120 ^oC (tartarate salt)

Seloken H₂O Solubility

16.9 mg/mL

Seloken State

Solid

Seloken LogP

2.477

Seloken Dosage Forms

Tablet

Seloken Indication

For the treatment of hypertension and angina pectoris.

Seloken Pharmacology

Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).

Seloken Absorption

Rapid and complete, 50%

Seloken side effects and Toxicity

LD₅₀=5500 mg/kg (orally in rats), toxic effects include bradycardia, hypotension, bronchospasm, and cardiac failure. LD₅₀=2090 mg/kg (orally in mice)

Seloken Patient Information

Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This medication can also be used to treat a heart condition called angina. This particular formulation is an extended release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is important to inform all your healthcare providers that you are taking this medication, especially before any surgeries or procedures.

Seloken Organisms Affected

Humans and other mammals