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Clarinex-D 12 Hour Extended Release Tablets (desloratadine + pseudoephedrine) Actifed DM Syrup (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Actifed DM Tablets (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Actifed Plus Caplet (Acetaminophen + Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Actifed Syrup (Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Actifed Tablets (Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Allergy Sinus Medication - Caplet (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Benadryl Decongestant Tablets (Diphenhydramine Hydrochloride + Pseudoephedrine Hydrochloride) Benylin 4 Flu - Syrup (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Benylin Codeine 3.3mg de Syr (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Bronchodex Pediatrique (Dextromethorphan Hydrobromide + Guaifenesin + Pheniramine Maleate + Pseudoephedrine Hydrochloride) Calmylin #2 Syr (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Calmylin #3 Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Codeine D-E Syr (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Cough and Flu Liq (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Pediatric Syrup (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Centracol Pediatrique - Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pheniramine Maleate + Pseudoephedrine Hydrochloride) Children's Tussin Cough Medicine DM Antitussive Decongestant (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Children's Tylenol Allergy - D Chewable Tablets (Acetaminophen + Diphenhydramine Hydrochloride + Pseudoephedrine Hydrochloride) Children's Tylenol Allergy-D Suspension (Acetaminophen + Diphenhydramine Hydrochloride + Pseudoephedrine Hydrochloride) Children's Tylenol Cold Liquid (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Children's Tylenol Cold Liquid with DM (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Children's Tylenol Sinus Chewable Tablet (Acetaminophen + Pseudoephedrine Hydrochloride) Claritin Allergy + Sinus Extra Strength (Loratadine + Pseudoephedrine Sulfate) Cold/Flu Relief (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Contac Day & Night Sinus/Allergy Caplet (Acetaminophen + Diphenhydramine Hydrochloride + Pseudoephedrine Hydrochloride) Contac-C Ext.Stren.Night Time Cough,Cold&Flu (Acetaminophen + Diphenhydramine Hydrochloride + Pseudoephedrine Hydrochloride) Cotrifed (Codeine Phosphate + Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Cough and Flu Syrup (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syr W.Cod. Pseudoephed.Hcl Guaifenesin (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup DM Decongestant (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Cough Syrup DM Decongestant Expectorant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup DM Decongestant for Children (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Cough Syrup DM-D-E (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dayquil Liquicaps - Cap (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Dayquil Liquicaps (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dayquil Medicine - Liq (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Daytime Cold & Flu Liquid Capsules (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Daytime Liquid - Liq (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Demdec Syr (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Dimetapp Children's Cough and Cold Liquid (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride) DM Cough Syrup Decongestant (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) DM Plus Decongestant Cough Syrup (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) DM Plus Decongestant Plus Expector.Ex.St.Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) DM Plus Decongestant Plus Expectorant Cough Syrup (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) DM-D-Expectorant Cough and Cold Syrup (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride) Extra Strength Allergy Plus Sinus Relief (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Extra Strength Allergy Sinus Medication (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Extra Strength Cold Medication Daytime Rlf (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Daytime Cold Relief-Caplet (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Nighttime Cold Relief-Caplet (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Sinus Medication-Caplet (Acetaminophen + Pseudoephedrine Hydrochloride) Extra Strength Sinus Relief-Caplet (Acetaminophen + Pseudoephedrine Hydrochloride) Extra Strength Tylenol Cold and Flu Powder (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Tylenol Sinus Nighttime Caplet (Acetaminophen + Doxylamine Succinate + Pseudoephedrine Hydrochloride) Ibuprofen and Pseudoephedrine (Ibuprofen + Pseudoephedrine Hydrochloride) Koffex DM + Decongestant Syrup (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Koffex DM + Decongestant + Expectorant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Koffex DM + Decongestant + Expectorant Extra Strength (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Koffex DM-D-E - Liq (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Medicament Sinus Personnel Ex-Fort Caplet (Acetaminophen + Pseudoephedrine Hydrochloride) Medicament Sinus Personnel Reg Caplet (Acetaminophen + Pseudoephedrine Hydrochloride) Nasal Decongestant Antihistamine (Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Neo Citran Daycaps Extra Strength - Caplet (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Nighttime Cold and Flu Liquid Capsules (Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Pseudoephedrine Hydrochloride) Nighttime Cold and Flu Relief (Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Pseudoephedrine Hydrochloride) Nitetime Cold Medicine (Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Pseudoephedrine Hydrochloride) Novahistex DM Expectorant with Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Novahistex DM with Decongestant (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Novahistex Expectorant with Decongestant (Guaifenesin + Pseudoephedrine Hydrochloride) Novahistine DM Expectorant with Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Novahistine DM with Decongestant - Liq (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Nyquil Liquicaps (Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Pseudoephedrine Hydrochloride) Once-a-Day Benylin Cold Cap (Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Pediatric Cough Syrup (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Personnelle DM Syr (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Promatussin DM Adult Formula Syr (Dextromethorphan Hydrobromide + Promethazine Hydrochloride + Pseudoephedrine Hydrochloride) Promatussin DM Children Formula (Dextromethorphan Hydrobromide + Promethazine Hydrochloride + Pseudoephedrine Hydrochloride) Pulmosirum Decongestionnant Sirop (Beechwood Creosote + Cocillana + Eucalyptus + Guaiacol + Ipecac + Lobelia Inflata + Menthol + Myroxylon Balsamum + Pseudoephedrine Hydrochloride + White Pine) Reg.Str.Cold Medic.(Night Time Relief)Caplet (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Regular Strength Cold Medication(Daytime R.) (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Regular Strength Sinus Medication (Acetaminophen + Pseudoephedrine Hydrochloride) Regular Strength Sinus Medication-Caplet (Acetaminophen + Pseudoephedrine Hydrochloride) Regular Strength Tylenol Cold and Flu Powder (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Regular Strength Tylenol Cold Chest Congestion (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Regular Strength Tylenol Cough Suspension with Decongestant (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Robitussin Honey Cough and Cold (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Robitussin Honey Flu (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Sinus, Pain & Nasal Congest Relief Caplet (Acetaminophen + Pseudoephedrine Hydrochloride) Sinutab N.T. Regular Strength Caplets (Acetaminophen + Diphenhydramine Hydrochloride + Pseudoephedrine Hydrochloride) Sudafed Cold and Cough Extra Strength Caplet (Acetaminophen + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Sudafed Cold and Flu Gel Caps (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Sudafed DM (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Sudafed Head Cold and Sinus Extra Strength Caplets (Acetaminophen + Pseudoephedrine Hydrochloride) Sudafed Sinus Extra Strength (Acetaminophen + Pseudoephedrine Hydrochloride) Theraflu Flu Cold and Cough Medicine (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Triaminic Cold and Allergy (Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Triaminic Decongest+Expect Liqui-Gels Cap (Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic DM Expectorant Syr (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic DM Plus Decongestant Syrup (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Triaminic DM+Decongestant Liqui-Gels Capsules (Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Triaminic Expectorant Syr (Chlorpheniramine Maleate + Guaifenesin + Pseudoephedrine Hydrochloride) Triaminicol DM Syrup (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Triprofed Tab (Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride) Tussin Cough Medicine DM Antitussive Expectorant Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride)
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Formula chimica
C10H15NO
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RX link
http://www.rxlist.com/cgi/generic/sudafed.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
Nessuna informazione disponibile
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Peso molecolare
165.232 g/mol
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Temperatura di fusione
117 - 118 oC
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H2O Solubilita
7 mg / L
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Stato
Solid
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LogP
1.507
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Forme di dosaggio
Capsule (rilascio prolungato); Tablet; Tablet (a rilascio prolungato); orale liquido, spray nasale, sciroppo
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Indicazione
Per il trattamento della congestione nasale, congestione sinusale, congestione della tuba di Eustachio, e rinite vasomotoria, e in aggiunta ad altri farmaci per il trattamento ottimale della rinite allergica, laringite, sinusite, otite media, e tracheobronchite. Utilizzato anche come terapia di prima linea del priapismo.
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Farmacologia
La pseudoefedrina è un agente simpaticomimetico, strutturalmente simile a efedrina, usati per alleviare la congestione nasale e sinusale e ridurre aria legati ai viaggi otalgia negli adulti. La pseudoefedrina cloridrato sali e solfato di pseudoefedrina si trovano in molti over-the-counter preparati sia come singolo ingrediente preparati, o più comunemente in combinazione con antistaminici e / o paracetamolo / ibuprofene. A differenza di antistaminici, che modificano la sistemica istamina mediata risposta allergica, pseudoefedrina serve solo ad alleviare la congestione nasale comunemente associati a raffreddori o allergie. Il vantaggio di orali pseudoefedrina più preparati topici nasali, come ossimetazolina, è che non causa congestione di rimbalzo (rinite medicamentosa).
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Assorbimento
Pseudoefedrina è facilmente e quasi completamente assorbito dal tratto gastrointestinale e non vi è alcuna evidenza di metabolismo di primo passaggio.
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Tossicita
Reazioni avverse comuni sono nervosismo, irrequietezza e insonnia. Rare reazioni avverse comprendono difficile / minzione dolorosa, vertigini / capogiri, palpitazioni, cefalea, aumento della sudorazione, nausea / vomito, tremori, difficoltà respiratoria, pallore insolito, e debolezza.
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Informazioni paziente
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Atto interessato organismi
Gli esseri umani e altri mammiferi