Dimetapp Decongestant Pediatric Drops
Brand names,
Dimetapp Decongestant Pediatric Drops
Analogs
Dimetapp Decongestant Pediatric Drops
Brand Names Mixture
Dimetapp Decongestant Pediatric Drops
Chemical_Formula
C10H15NO
Dimetapp Decongestant Pediatric Drops
RX_link
http://www.rxlist.com/cgi/generic/sudafed.htm
Dimetapp Decongestant Pediatric Drops
fda sheet
Dimetapp Decongestant Pediatric Drops
msds (material safety sheet)
Dimetapp Decongestant Pediatric Drops
Synthesis Reference
No information avaliable
Dimetapp Decongestant Pediatric Drops
Molecular Weight
165.232 g/mol
Dimetapp Decongestant Pediatric Drops
Melting Point
117 - 118 oC
Dimetapp Decongestant Pediatric Drops
H2O Solubility
7 mg/L
Dimetapp Decongestant Pediatric Drops
State
Solid
Dimetapp Decongestant Pediatric Drops
LogP
1.507
Dimetapp Decongestant Pediatric Drops
Dosage Forms
Capsule (sustained-release); Tablet; Tablet (extended-release); Oral liquid; Nasal spray; Syrup
Dimetapp Decongestant Pediatric Drops
Indication
For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.
Dimetapp Decongestant Pediatric Drops
Pharmacology
Pseudoephedrine is a sympathomimetic agent, structurally similar to ephedrine, used to relieve nasal and sinus congestion and reduce air-travel-related otalgia in adults. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines and/or paracetamol/ibuprofen. Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only serves to relieve nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa).
Dimetapp Decongestant Pediatric Drops
Absorption
Pseudoephedrine is readily and almost completely absorbed from the GI tract and there is no evidence of first-pass metabolism.
Dimetapp Decongestant Pediatric Drops
side effects and Toxicity
Common adverse reactions include nervousness, restlessness, and insomnia. Rare adverse reactions include difficult/painful urination, dizziness/lightheadedness, heart palpitations, headache, increased sweating, nausea/vomiting, trembling, troubled breathing, unusual paleness, and weakness.
Dimetapp Decongestant Pediatric Drops
Patient Information
Dimetapp Decongestant Pediatric Drops
Organisms Affected
Humans and other mammals