Maxenal
Brand names,
Maxenal
Analogs
Maxenal
Brand Names Mixture
Maxenal
Chemical_Formula
C10H15NO
Maxenal
RX_link
http://www.rxlist.com/cgi/generic/sudafed.htm
Maxenal
fda sheet
Maxenal
msds (material safety sheet)
Maxenal
Synthesis Reference
No information avaliable
Maxenal
Molecular Weight
165.232 g/mol
Maxenal
Melting Point
117 - 118 oC
Maxenal
H2O Solubility
7 mg/L
Maxenal
State
Solid
Maxenal
LogP
1.507
Maxenal
Dosage Forms
Capsule (sustained-release); Tablet; Tablet (extended-release); Oral liquid; Nasal spray; Syrup
Maxenal
Indication
For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.
Maxenal
Pharmacology
Pseudoephedrine is a sympathomimetic agent, structurally similar to ephedrine, used to relieve nasal and sinus congestion and reduce air-travel-related otalgia in adults. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines and/or paracetamol/ibuprofen. Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only serves to relieve nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa).
Maxenal
Absorption
Pseudoephedrine is readily and almost completely absorbed from the GI tract and there is no evidence of first-pass metabolism.
Maxenal
side effects and Toxicity
Common adverse reactions include nervousness, restlessness, and insomnia. Rare adverse reactions include difficult/painful urination, dizziness/lightheadedness, heart palpitations, headache, increased sweating, nausea/vomiting, trembling, troubled breathing, unusual paleness, and weakness.
Maxenal
Patient Information
Maxenal
Organisms Affected
Humans and other mammals