Efidac 24 Pseudoephedrine Hcl
Brand names,
Efidac 24 Pseudoephedrine Hcl
Analogs
Efidac 24 Pseudoephedrine Hcl
Brand Names Mixture
Efidac 24 Pseudoephedrine Hcl
Chemical_Formula
C10H15NO
Efidac 24 Pseudoephedrine Hcl
RX_link
http://www.rxlist.com/cgi/generic/sudafed.htm
Efidac 24 Pseudoephedrine Hcl
fda sheet
Efidac 24 Pseudoephedrine Hcl
msds (material safety sheet)
Efidac 24 Pseudoephedrine Hcl
Synthesis Reference
No information avaliable
Efidac 24 Pseudoephedrine Hcl
Molecular Weight
165.232 g/mol
Efidac 24 Pseudoephedrine Hcl
Melting Point
117 - 118 oC
Efidac 24 Pseudoephedrine Hcl
H2O Solubility
7 mg/L
Efidac 24 Pseudoephedrine Hcl
State
Solid
Efidac 24 Pseudoephedrine Hcl
LogP
1.507
Efidac 24 Pseudoephedrine Hcl
Dosage Forms
Capsule (sustained-release); Tablet; Tablet (extended-release); Oral liquid; Nasal spray; Syrup
Efidac 24 Pseudoephedrine Hcl
Indication
For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.
Efidac 24 Pseudoephedrine Hcl
Pharmacology
Pseudoephedrine is a sympathomimetic agent, structurally similar to ephedrine, used to relieve nasal and sinus congestion and reduce air-travel-related otalgia in adults. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines and/or paracetamol/ibuprofen. Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only serves to relieve nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa).
Efidac 24 Pseudoephedrine Hcl
Absorption
Pseudoephedrine is readily and almost completely absorbed from the GI tract and there is no evidence of first-pass metabolism.
Efidac 24 Pseudoephedrine Hcl
side effects and Toxicity
Common adverse reactions include nervousness, restlessness, and insomnia. Rare adverse reactions include difficult/painful urination, dizziness/lightheadedness, heart palpitations, headache, increased sweating, nausea/vomiting, trembling, troubled breathing, unusual paleness, and weakness.
Efidac 24 Pseudoephedrine Hcl
Patient Information
Efidac 24 Pseudoephedrine Hcl
Organisms Affected
Humans and other mammals