Sudafed 12 Hour
Brand names,
Sudafed 12 Hour
Analogs
Sudafed 12 Hour
Brand Names Mixture
Sudafed 12 Hour
Chemical_Formula
C10H15NO
Sudafed 12 Hour
RX_link
http://www.rxlist.com/cgi/generic/sudafed.htm
Sudafed 12 Hour
fda sheet
Sudafed 12 Hour
msds (material safety sheet)
Sudafed 12 Hour
Synthesis Reference
No information avaliable
Sudafed 12 Hour
Molecular Weight
165.232 g/mol
Sudafed 12 Hour
Melting Point
117 - 118 oC
Sudafed 12 Hour
H2O Solubility
7 mg/L
Sudafed 12 Hour
State
Solid
Sudafed 12 Hour
LogP
1.507
Sudafed 12 Hour
Dosage Forms
Capsule (sustained-release); Tablet; Tablet (extended-release); Oral liquid; Nasal spray; Syrup
Sudafed 12 Hour
Indication
For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.
Sudafed 12 Hour
Pharmacology
Pseudoephedrine is a sympathomimetic agent, structurally similar to ephedrine, used to relieve nasal and sinus congestion and reduce air-travel-related otalgia in adults. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines and/or paracetamol/ibuprofen. Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only serves to relieve nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa).
Sudafed 12 Hour
Absorption
Pseudoephedrine is readily and almost completely absorbed from the GI tract and there is no evidence of first-pass metabolism.
Sudafed 12 Hour
side effects and Toxicity
Common adverse reactions include nervousness, restlessness, and insomnia. Rare adverse reactions include difficult/painful urination, dizziness/lightheadedness, heart palpitations, headache, increased sweating, nausea/vomiting, trembling, troubled breathing, unusual paleness, and weakness.
Sudafed 12 Hour
Patient Information
Sudafed 12 Hour
Organisms Affected
Humans and other mammals