Siplarol
Categorie
Siplarol Les marques, Siplarol Analogs
Siplarol Les marques melange
Siplarol Formule chimique
C23H25F3N2OS
Siplarol RX lien
No information avaliable
Siplarol FDA fiche
Siplarol msds (fiche de securite des materiaux)
Siplarol Synthese de reference
PN Craig, CL Zirkle, le brevet américain. 3.282.930 (1966 à SKF)
Siplarol Poids moleculaire
434.519 g/mol
Siplarol Point de fusion
No information avaliable
Siplarol H2O Solubilite
0.000346 mg / ml
Siplarol Etat
Solid
Siplarol LogP
4.694
Siplarol Formes pharmaceutiques
Tablet; injection IM
Siplarol Indication
Pour une utilisation dans le traitement de la schizophrénie et la dépression
Siplarol Pharmacologie
Flupenthixol est un anxiolytique, antidépressive et l'agent stabilisateur de l'humeur. Il inhibe les récepteurs centraux des monoamines, en particulier la dopamine D1 et les récepteurs D2. Par conséquent, il augmente la quantité de sérotonine et de noradrénaline que l'humeur de contrôle et de la pensée, et améliore l'humeur.
Siplarol Absorption
Assez lente et incomplète après administration orale
Siplarol Toxicite
DL50 = 300 mk / kg (voie orale chez la souris); DL50 = 791 mg / kg (voie orale chez le rat); DL50 = 87 mk / kg (IV chez la souris); DL50 = 37 mg / kg (IV chez le rat)
Siplarol Information pour les patients
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Siplarol Organismes affectes
Les humains et autres mammifères
