Siplaril
Categorie
Siplaril Les marques, Siplaril Analogs
Siplaril Les marques melange
Siplaril Formule chimique
C23H25F3N2OS
Siplaril RX lien
No information avaliable
Siplaril FDA fiche
Siplaril msds (fiche de securite des materiaux)
Siplaril Synthese de reference
PN Craig, CL Zirkle, le brevet américain. 3.282.930 (1966 à SKF)
Siplaril Poids moleculaire
434.519 g/mol
Siplaril Point de fusion
No information avaliable
Siplaril H2O Solubilite
0.000346 mg / ml
Siplaril Etat
Solid
Siplaril LogP
4.694
Siplaril Formes pharmaceutiques
Tablet; injection IM
Siplaril Indication
Pour une utilisation dans le traitement de la schizophrénie et la dépression
Siplaril Pharmacologie
Flupenthixol est un anxiolytique, antidépressive et l'agent stabilisateur de l'humeur. Il inhibe les récepteurs centraux des monoamines, en particulier la dopamine D1 et les récepteurs D2. Par conséquent, il augmente la quantité de sérotonine et de noradrénaline que l'humeur de contrôle et de la pensée, et améliore l'humeur.
Siplaril Absorption
Assez lente et incomplète après administration orale
Siplaril Toxicite
DL50 = 300 mk / kg (voie orale chez la souris); DL50 = 791 mg / kg (voie orale chez le rat); DL50 = 87 mk / kg (IV chez la souris); DL50 = 37 mg / kg (IV chez le rat)
Siplaril Information pour les patients
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Siplaril Organismes affectes
Les humains et autres mammifères
