Nergadan
Categorie
Nergadan Les marques, Nergadan Analogs
- 6 alpha-Methylcompactin
- Altocor
- Altoprev
- Artein
- Belvas
- Cholestra
- Closterol
- Colevix
- Compactin
- Hipolip
- Hipovastin
- Lestatin
- Lipdip
- Lipivas
- Lipofren
- Lovalip
- Lovalord
- Lovastatin [Usan:Ban:Inn]
- Lovastatina [Spanish]
- Lovastatine [French]
- Lovastatinum [Latin]
- Lovasterol
- Lovastin
- Lozutin
- Mevacor
- Mevastatin
- Mevinacor
- Mevinolin
- Mevlor
- Monacolin K
- Nergadan
- Paschol
- Pravastatin
- Rodatin
- Rovacor
- Sivlor
- Taucor
- Tecnolip
- Teroltrat
Nergadan Les marques melange
Nergadan Formule chimique
C24H36O5
Nergadan RX lien
http://www.rxlist.com/cgi/generic3/altocor.htm
Nergadan FDA fiche
Nergadan msds (fiche de securite des materiaux)
Nergadan Synthese de reference
RL Monaghan et al., US. 4,231,938 (1980)
Nergadan Poids moleculaire
404.54 g/mol
Nergadan Point de fusion
174.5 oC
Nergadan H2O Solubilite
0,0004 mg / ml
Nergadan Etat
Solid
Nergadan LogP
4
Nergadan Formes pharmaceutiques
Tablet
Nergadan Indication
Pour la gestion en tant que complément d'un régime pour réduire élevées au total-C, le C-LDL, l'apo B, et les taux de TG chez les patients atteints d'hypercholestérolémie primaire et de dyslipidémie mixte; Pour la prévention primaire des maladies coronariennes
Nergadan Pharmacologie
Lovastatine, un agent antilipémique produit par fermentation de Aspergillus terreus, est le premier d'une classe d'agents hypolipémiants appelés les inhibiteurs de la HMG-CoA réductase. La lovastatine est utilisée pour traiter l'hypercholestérolémie, de ralentir l'athérosclérose coronarienne, et pour prévenir l'infarctus du myocarde et d'AVC. Lovastatine, comme simvastin et contrairement à la pravastatine, est une prodrogue, en se concentrant médicament actif dans le foie au cours du premier passage de circulation.
Nergadan Absorption
30%
Nergadan Toxicite
DL50> 1000 mg / kg (par voie orale chez la souris)
Nergadan Information pour les patients
PATIENT INFORMATION
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Nergadan Organismes affectes
Les humains et autres mammifères
