Categorie
Metroprolol
Les marques,
Metroprolol
Analogs
Metroprolol
Les marques melange
LOPRESSOR HCT
Metroprolol
Formule chimique
C15H25NO3
Metroprolol
RX lien
http://www.rxlist.com/cgi/generic/metopxl.htm
Metroprolol
FDA fiche
Metroprolol
msds (fiche de securite des materiaux)
Metroprolol
Synthese de reference
AE Brandstorm et al., US. 3,873,600 (1975)
Metroprolol
Poids moleculaire
267.364 g/mol
Metroprolol
Point de fusion
120 oC (tartarate salt)
Metroprolol
H2O Solubilite
16,9 mg / ml
Metroprolol
Etat
Solid
Metroprolol
LogP
2.477
Metroprolol
Formes pharmaceutiques
Tablet
Metroprolol
Indication
Pour le traitement de l'hypertension et l'angine de poitrine.
Metroprolol
Pharmacologie
Métoprolol, un antagoniste compétitif, beta1-adrénergiques sélectifs (cardiosélectif), est similaire à l'aténolol dans sa liposolubilité modérée, manque d'activité sympathomimétique intrinsèque (ASI), et la membrane faibles stabilisation de l'activité (MSA).
Metroprolol
Absorption
Rapide et complète, 50%
Metroprolol
Toxicite
DL50 = 5500 mg / kg (par voie orale chez le rat), les effets toxiques incluent la bradycardie, l'hypotension, bronchospasme et insuffisance cardiaque. DL50 = 2090 mg / kg (par voie orale chez la souris)
Metroprolol
Information pour les patients
Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This
medication can also be used to treat a heart condition called angina. This particular formulation is an extended
release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or
right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This
medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this
medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble
breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is
important to inform all your healthcare providers that you are taking this medication, especially before any
surgeries or procedures.
Metroprolol
Organismes affectes
Les humains et autres mammifères