Lipofren
Categoria
Lipofren Nombres de marca, Lipofren Analogos
- 6 alpha-Methylcompactin
- Altocor
- Altoprev
- Artein
- Belvas
- Cholestra
- Closterol
- Colevix
- Compactin
- Hipolip
- Hipovastin
- Lestatin
- Lipdip
- Lipivas
- Lipofren
- Lovalip
- Lovalord
- Lovastatin [Usan:Ban:Inn]
- Lovastatina [Spanish]
- Lovastatine [French]
- Lovastatinum [Latin]
- Lovasterol
- Lovastin
- Lozutin
- Mevacor
- Mevastatin
- Mevinacor
- Mevinolin
- Mevlor
- Monacolin K
- Nergadan
- Paschol
- Pravastatin
- Rodatin
- Rovacor
- Sivlor
- Taucor
- Tecnolip
- Teroltrat
Lipofren Marca los nombres de mezcla
Lipofren Formula quimica
C24H36O5
Lipofren RX enlace
http://www.rxlist.com/cgi/generic3/altocor.htm
Lipofren FDA hoja
Lipofren MSDS (hoja de seguridad de materiales)
Lipofren Sintesis de referencia
RL Monaghan et al., Patente de EE.UU.. 4,231,938 (1980)
Lipofren Peso molecular
404.54 g/mol
Lipofren Punto de fusion
174.5 oC
Lipofren H2O Solubilidad
0,0004 mg / mL
Lipofren Estado
Solid
Lipofren LogP
4
Lipofren Formas de dosificacion
Tableta
Lipofren Indicacion
Para la gestión como un complemento a la dieta para reducir los niveles de C-total, LDL-C, apo B, y los niveles de TG en pacientes con hipercolesterolemia primaria y dislipidemia mixta, para la prevención primaria de enfermedad coronaria
Lipofren Farmacologia
Lovastatina, un agente antilipémico producido por la fermentación de Aspergillus terreus, es el primero de una clase de agentes reductores de lípidos conocidos como los inhibidores de la HMG-CoA reductasa. La lovastatina se usa para tratar hipercolesterolemia, para frenar la aterosclerosis coronaria, y para prevenir el infarto de miocardio y accidente cerebrovascular. Lovastatina, como simvastin ya diferencia de pravastatina, es un profármaco, la concentración de fármaco activo en la hígado durante el primer paso de la circulación.
Lipofren Absorcion
30%
Lipofren Toxicidad
DL50> 1000 mg / kg (por vía oral en ratones)
Lipofren Informacion de Pacientes
PATIENT INFORMATION
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Lovastatin is used to lower high cholesterol levels. This medication should
not be taken if you are pregnant, nursing, or have liver disease. Lovastatin
should be taken with the evening meal. This medication may cause increased
sensitivity to sunlight. Use sunscreens and wear protective clothing until
degree of sensitivity is determined. Notify your physician if you develop
blurred vision; skin rash; muscle pain, weakness, or cramps; unexplained fever,
or yellowing of the skin or eyes.
Patients should be advised about substances they should not take concomitantly
with lovastatin and be advised to report promptly unexplained muscle pain,
tenderness, or weakness (see list below and WARNINGS, Myopathy/Rhabdomyolysis ).
Patients should also be advised to inform other physicians prescribing a new
medication that they are taking MEVACOR .
Lipofren Organismos afectados
Humanos y otros mamíferos
