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Urolit Brand names, Urolit Analogs

Urolit Brand Names Mixture

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Urolit Chemical_Formula


Urolit RX_link


Urolit fda sheet


Urolit msds (material safety sheet)

Urolit MSDS

Urolit Synthesis Reference

Robins, J. Am. Chem. So. 78, 784 (1956)

Urolit Molecular Weight

136.112 g/mol

Urolit Melting Point

350 oC

Urolit H2O Solubility

569 mg/L

Urolit State


Urolit LogP


Urolit Dosage Forms

Tablet for oral administration (100mg, 200mg and 300mg); Injection

Urolit Indication

For the treatment of hyperuricemia associated with primary or secondary gout.

Urolit Pharmacology

Allopurinol, a structural analog of the natural purine base hypoxanthine, is used to prevent gout and renal calculi due to either uric acid or calcium oxalate and to treat uric acid nephropathy, hyperuricemia, and some solid tumors.

Urolit Absorption

Approximately 90% absorbed from the gastrointestinal tract.

Urolit side effects and Toxicity

LD50=214 mg/kg (in mice)

Urolit Patient Information

Patients should be informed of the following:

1. They should be cautioned to discontinue allopurinol and to consult their physician immediately at the first sign of a skin rash, painful urination, blood in the urine, irritation of the eyes, or swelling of the lips or mouth.
2. They should be reminded to continue drug therapy prescribed for gouty attacks since optimal benefit of allopurinol may be delayed for two to six weeks.
3. They should be encouraged to increase fluid intake during therapy to prevent renal stones.
4. If a single dose of allopurinol is occasionally forgotten, there is no need to double the dose at the next scheduled time.
5. There may be certain risks associated with the concomitant use of allopurinol and dicumarol, sulfinpyrazone, mercaptopurine, azathioprine, ampicillin, amoxicillin and thiazide diuretics, and they should follow the instructions of their physician.
6. Due to the occasional occurrence of drowsiness, patients should take precautions when engaging in activities where alertness is mandatory.
7. Patients may wish to take allopurinol after meals to minimize gastric irritation.

Urolit Organisms Affected

Humans and other mammals