Triclordiuride
Triclordiuride Brand names, Triclordiuride Analogs
- Achletin
- Anatran
- Anistadin
- Aponorin
- Carvacron
- Chlopolidine
- Cretonin
- Diu-Hydrin
- Diurazida
- Diurese
- Diuroral
- Esmarin
- Eurinol
- Fluitran
- Flurese
- Flutra
- Gangesol
- Hydrotrichlorothiazide
- Intromene
- Isestran
- Kubacron
- Metahydrin
- Metatensin
- Metatensin #2
- Metatensin #4
- Nakva
- Naqua
- Naquasone
- Naquival
- Salurin
- Schebitran
- Tachionin
- Tolcasone
- Trichlorex
- Trichlormas
- Trichlormetazid
- Trichlormethiazid
- Trichlormethiazide W/ Reserpine
- Trichloromethiadiazide
- Trichloromethiazide
- Triclordiuride
- Triclormetiazide
- Triflumen
Triclordiuride Brand Names Mixture
- No information avaliable
Triclordiuride Chemical_Formula
C8H8Cl3N3O4S2
Triclordiuride RX_link
No information avaliable
Triclordiuride fda sheet
Triclordiuride msds (material safety sheet)
Triclordiuride Synthesis Reference
No information avaliable
Triclordiuride Molecular Weight
380.657 g/mol
Triclordiuride Melting Point
No information avaliable
Triclordiuride H2O Solubility
No information avaliable
Triclordiuride State
Solid
Triclordiuride LogP
1.023
Triclordiuride Dosage Forms
No information avaliable
Triclordiuride Indication
Used in the treatment of oedema (including that associated with heart failure) and hypertension.
Triclordiuride Pharmacology
Trichloromethiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Trichloromethiazide has also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomer-ulonephritis, and chronic renal failure. Trichloromethiazide is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. Like other thiazides, Trichloromethiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Triclordiuride Absorption
No information avaliable
Triclordiuride side effects and Toxicity
Oral Rat LD50 = 5600 mg/kg, oral Mouse LD50 = 2600 mg/kg
Triclordiuride Patient Information
No information avaliable
Triclordiuride Organisms Affected
Humans and other mammals
