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Naquasone Brand names, Naquasone Analogs

Naquasone Brand Names Mixture

  • No information avaliable

Naquasone Chemical_Formula


Naquasone RX_link

No information avaliable

Naquasone fda sheet

Naquasone msds (material safety sheet)

Naquasone MSDS

Naquasone Synthesis Reference

No information avaliable

Naquasone Molecular Weight

380.657 g/mol

Naquasone Melting Point

No information avaliable

Naquasone H2O Solubility

No information avaliable

Naquasone State


Naquasone LogP


Naquasone Dosage Forms

No information avaliable

Naquasone Indication

Used in the treatment of oedema (including that associated with heart failure) and hypertension.

Naquasone Pharmacology

Trichloromethiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Trichloromethiazide has also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomer-ulonephritis, and chronic renal failure. Trichloromethiazide is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. Like other thiazides, Trichloromethiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Naquasone Absorption

No information avaliable

Naquasone side effects and Toxicity

Oral Rat LD50 = 5600 mg/kg, oral Mouse LD50 = 2600 mg/kg

Naquasone Patient Information

No information avaliable

Naquasone Organisms Affected

Humans and other mammals