Terconazole
Terconazole Brand names, Terconazole Analogs
Terconazole Brand Names Mixture
- No information avaliable
Terconazole Chemical_Formula
C26H31Cl2N5O3
Terconazole RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Terconazole fda sheet
Terconazole msds (material safety sheet)
Terconazole Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Terconazole Molecular Weight
532.462 g/mol
Terconazole Melting Point
126.3oC
Terconazole H2O Solubility
No information avaliable
Terconazole State
Solid
Terconazole LogP
5.361
Terconazole Dosage Forms
Vaginal cream; Vaginal suppositories
Terconazole Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Terconazole Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Terconazole Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Terconazole side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Terconazole Patient Information
Terconazole Organisms Affected
Fungi
