Terazol
Terazol Brand names, Terazol Analogs
Terazol Brand Names Mixture
- No information avaliable
Terazol Chemical_Formula
C26H31Cl2N5O3
Terazol RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Terazol fda sheet
Terazol msds (material safety sheet)
Terazol Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Terazol Molecular Weight
532.462 g/mol
Terazol Melting Point
126.3oC
Terazol H2O Solubility
No information avaliable
Terazol State
Solid
Terazol LogP
5.361
Terazol Dosage Forms
Vaginal cream; Vaginal suppositories
Terazol Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Terazol Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Terazol Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Terazol side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Terazol Patient Information
Terazol Organisms Affected
Fungi
