Terazol 3
Brand names,
Terazol 3
Analogs
Terazol 3
Brand Names Mixture
Terazol 3
Chemical_Formula
C26H31Cl2N5O3
Terazol 3
RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Terazol 3
fda sheet
Terazol 3
msds (material safety sheet)
Terazol 3
Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Terazol 3
Molecular Weight
532.462 g/mol
Terazol 3
Melting Point
126.3oC
Terazol 3
H2O Solubility
No information avaliable
Terazol 3
State
Solid
Terazol 3
LogP
5.361
Terazol 3
Dosage Forms
Vaginal cream; Vaginal suppositories
Terazol 3
Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Terazol 3
Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Terazol 3
Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Terazol 3
side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Terazol 3
Patient Information
Terazol 3
Organisms Affected
Fungi