Triaconazole
Triaconazole Brand names, Triaconazole Analogs
Triaconazole Brand Names Mixture
- No information avaliable
Triaconazole Chemical_Formula
C26H31Cl2N5O3
Triaconazole RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Triaconazole fda sheet
Triaconazole msds (material safety sheet)
Triaconazole Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Triaconazole Molecular Weight
532.462 g/mol
Triaconazole Melting Point
126.3oC
Triaconazole H2O Solubility
No information avaliable
Triaconazole State
Solid
Triaconazole LogP
5.361
Triaconazole Dosage Forms
Vaginal cream; Vaginal suppositories
Triaconazole Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Triaconazole Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Triaconazole Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Triaconazole side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Triaconazole Patient Information
Triaconazole Organisms Affected
Fungi
