Terazol 7
Brand names,
Terazol 7
Analogs
Terazol 7
Brand Names Mixture
Terazol 7
Chemical_Formula
C26H31Cl2N5O3
Terazol 7
RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Terazol 7
fda sheet
Terazol 7
msds (material safety sheet)
Terazol 7
Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Terazol 7
Molecular Weight
532.462 g/mol
Terazol 7
Melting Point
126.3oC
Terazol 7
H2O Solubility
No information avaliable
Terazol 7
State
Solid
Terazol 7
LogP
5.361
Terazol 7
Dosage Forms
Vaginal cream; Vaginal suppositories
Terazol 7
Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Terazol 7
Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Terazol 7
Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Terazol 7
side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Terazol 7
Patient Information
Terazol 7
Organisms Affected
Fungi