Tercospor
Brand names,
Tercospor
Analogs
Tercospor
Brand Names Mixture
Tercospor
Chemical_Formula
C26H31Cl2N5O3
Tercospor
RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Tercospor
fda sheet
Tercospor
msds (material safety sheet)
Tercospor
Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Tercospor
Molecular Weight
532.462 g/mol
Tercospor
Melting Point
126.3oC
Tercospor
H2O Solubility
No information avaliable
Tercospor
State
Solid
Tercospor
LogP
5.361
Tercospor
Dosage Forms
Vaginal cream; Vaginal suppositories
Tercospor
Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Tercospor
Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Tercospor
Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Tercospor
side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Tercospor
Patient Information
Tercospor
Organisms Affected
Fungi