Gyno-Terazol
Brand names,
Gyno-Terazol
Analogs
Gyno-Terazol
Brand Names Mixture
Gyno-Terazol
Chemical_Formula
C26H31Cl2N5O3
Gyno-Terazol
RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Gyno-Terazol
fda sheet
Gyno-Terazol
msds (material safety sheet)
Gyno-Terazol
Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Gyno-Terazol
Molecular Weight
532.462 g/mol
Gyno-Terazol
Melting Point
126.3oC
Gyno-Terazol
H2O Solubility
No information avaliable
Gyno-Terazol
State
Solid
Gyno-Terazol
LogP
5.361
Gyno-Terazol
Dosage Forms
Vaginal cream; Vaginal suppositories
Gyno-Terazol
Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Gyno-Terazol
Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Gyno-Terazol
Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Gyno-Terazol
side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Gyno-Terazol
Patient Information
Gyno-Terazol
Organisms Affected
Fungi