Fungistat
Fungistat Brand names, Fungistat Analogs
Fungistat Brand Names Mixture
- No information avaliable
Fungistat Chemical_Formula
C26H31Cl2N5O3
Fungistat RX_link
http://www.rxlist.com/cgi/generic/tercon.htm
Fungistat fda sheet
Fungistat msds (material safety sheet)
Fungistat Synthesis Reference
J. Heeres et al., U.S. Pat. 4,144,346 (1979)
Fungistat Molecular Weight
532.462 g/mol
Fungistat Melting Point
126.3oC
Fungistat H2O Solubility
No information avaliable
Fungistat State
Solid
Fungistat LogP
5.361
Fungistat Dosage Forms
Vaginal cream; Vaginal suppositories
Fungistat Indication
Candidiasis (a yeast-like fungal infection) of the vulva and vagina.
Fungistat Pharmacology
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring.
Fungistat Absorption
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations
Fungistat side effects and Toxicity
The oral LD50 values were found to be 1741 and 849 mg/kg for the male and female in rat.
Fungistat Patient Information
Fungistat Organisms Affected
Fungi
