Sufentanil
Brand names,
Sufentanil
Analogs
Sufentanil
Brand Names Mixture
Sufentanil
Chemical_Formula
C22H30N2O2S
Sufentanil
RX_link
No information avaliable
Sufentanil
fda sheet
Sufentanil
msds (material safety sheet)
Sufentanil
Synthesis Reference
No information avaliable
Sufentanil
Molecular Weight
386.552 g/mol
Sufentanil
Melting Point
97 oC
Sufentanil
H2O Solubility
76 mg/L
Sufentanil
State
Solid
Sufentanil
LogP
3.382
Sufentanil
Dosage Forms
Liquid; Solution
Sufentanil
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Sufentanil
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Sufentanil
Absorption
No information avaliable
Sufentanil
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Sufentanil
Patient Information
Sufentanil
Organisms Affected
Humans and other mammals