Sufentanil Citrate
Brand names,
Sufentanil Citrate
Analogs
Sufentanil Citrate
Brand Names Mixture
Sufentanil Citrate
Chemical_Formula
C22H30N2O2S
Sufentanil Citrate
RX_link
No information avaliable
Sufentanil Citrate
fda sheet
Sufentanil Citrate
msds (material safety sheet)
Sufentanil Citrate
Synthesis Reference
No information avaliable
Sufentanil Citrate
Molecular Weight
386.552 g/mol
Sufentanil Citrate
Melting Point
97 oC
Sufentanil Citrate
H2O Solubility
76 mg/L
Sufentanil Citrate
State
Solid
Sufentanil Citrate
LogP
3.382
Sufentanil Citrate
Dosage Forms
Liquid; Solution
Sufentanil Citrate
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Sufentanil Citrate
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Sufentanil Citrate
Absorption
No information avaliable
Sufentanil Citrate
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Sufentanil Citrate
Patient Information
Sufentanil Citrate
Organisms Affected
Humans and other mammals