Sufentanyl
Brand names,
Sufentanyl
Analogs
Sufentanyl
Brand Names Mixture
Sufentanyl
Chemical_Formula
C22H30N2O2S
Sufentanyl
RX_link
No information avaliable
Sufentanyl
fda sheet
Sufentanyl
msds (material safety sheet)
Sufentanyl
Synthesis Reference
No information avaliable
Sufentanyl
Molecular Weight
386.552 g/mol
Sufentanyl
Melting Point
97 oC
Sufentanyl
H2O Solubility
76 mg/L
Sufentanyl
State
Solid
Sufentanyl
LogP
3.382
Sufentanyl
Dosage Forms
Liquid; Solution
Sufentanyl
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Sufentanyl
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Sufentanyl
Absorption
No information avaliable
Sufentanyl
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Sufentanyl
Patient Information
Sufentanyl
Organisms Affected
Humans and other mammals