Sufentanil Base
Brand names,
Sufentanil Base
Analogs
Sufentanil Base
Brand Names Mixture
Sufentanil Base
Chemical_Formula
C22H30N2O2S
Sufentanil Base
RX_link
No information avaliable
Sufentanil Base
fda sheet
Sufentanil Base
msds (material safety sheet)
Sufentanil Base
Synthesis Reference
No information avaliable
Sufentanil Base
Molecular Weight
386.552 g/mol
Sufentanil Base
Melting Point
97 oC
Sufentanil Base
H2O Solubility
76 mg/L
Sufentanil Base
State
Solid
Sufentanil Base
LogP
3.382
Sufentanil Base
Dosage Forms
Liquid; Solution
Sufentanil Base
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Sufentanil Base
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Sufentanil Base
Absorption
No information avaliable
Sufentanil Base
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Sufentanil Base
Patient Information
Sufentanil Base
Organisms Affected
Humans and other mammals