Dea No. 9740
Brand names,
Dea No. 9740
Analogs
Dea No. 9740
Brand Names Mixture
Dea No. 9740
Chemical_Formula
C22H30N2O2S
Dea No. 9740
RX_link
No information avaliable
Dea No. 9740
fda sheet
Dea No. 9740
msds (material safety sheet)
Dea No. 9740
Synthesis Reference
No information avaliable
Dea No. 9740
Molecular Weight
386.552 g/mol
Dea No. 9740
Melting Point
97 oC
Dea No. 9740
H2O Solubility
76 mg/L
Dea No. 9740
State
Solid
Dea No. 9740
LogP
3.382
Dea No. 9740
Dosage Forms
Liquid; Solution
Dea No. 9740
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Dea No. 9740
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Dea No. 9740
Absorption
No information avaliable
Dea No. 9740
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Dea No. 9740
Patient Information
Dea No. 9740
Organisms Affected
Humans and other mammals