Sufenta
Brand names,
Sufenta
Analogs
Sufenta
Brand Names Mixture
Sufenta
Chemical_Formula
C22H30N2O2S
Sufenta
RX_link
No information avaliable
Sufenta
fda sheet
Sufenta
msds (material safety sheet)
Sufenta
Synthesis Reference
No information avaliable
Sufenta
Molecular Weight
386.552 g/mol
Sufenta
Melting Point
97 oC
Sufenta
H2O Solubility
76 mg/L
Sufenta
State
Solid
Sufenta
LogP
3.382
Sufenta
Dosage Forms
Liquid; Solution
Sufenta
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Sufenta
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Sufenta
Absorption
No information avaliable
Sufenta
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Sufenta
Patient Information
Sufenta
Organisms Affected
Humans and other mammals