Sulfentanil Citrate
Brand names,
Sulfentanil Citrate
Analogs
Sulfentanil Citrate
Brand Names Mixture
Sulfentanil Citrate
Chemical_Formula
C22H30N2O2S
Sulfentanil Citrate
RX_link
No information avaliable
Sulfentanil Citrate
fda sheet
Sulfentanil Citrate
msds (material safety sheet)
Sulfentanil Citrate
Synthesis Reference
No information avaliable
Sulfentanil Citrate
Molecular Weight
386.552 g/mol
Sulfentanil Citrate
Melting Point
97 oC
Sulfentanil Citrate
H2O Solubility
76 mg/L
Sulfentanil Citrate
State
Solid
Sulfentanil Citrate
LogP
3.382
Sulfentanil Citrate
Dosage Forms
Liquid; Solution
Sulfentanil Citrate
Indication
Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
Sulfentanil Citrate
Pharmacology
Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Sufentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Sufentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Sulfentanil Citrate
Absorption
No information avaliable
Sulfentanil Citrate
side effects and Toxicity
LD50: 18.7 mg/kg (IV in mice)
Sulfentanil Citrate
Patient Information
Sulfentanil Citrate
Organisms Affected
Humans and other mammals