Prilosec

Prilosec Brand names, Prilosec Analogs

Prilosec Brand Names Mixture

No information avaliable

Prilosec Chemical_Formula

C₁₇H₁₉N₃O₃S

Prilosec RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Prilosec fda sheet

Prilosec FDA

Prilosec msds (material safety sheet)

Prilosec Synthesis Reference

No information avaliable

Prilosec Molecular Weight

345.417 g/mol

Prilosec Melting Point

155 ^oC

Prilosec H₂O Solubility

Very slightly soluble in water

Prilosec State

Solid

Prilosec LogP

1.078

Prilosec Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Prilosec Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Prilosec Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Prilosec Absorption

90%

Prilosec side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Prilosec Patient Information