Esomperazole

Esomperazole Brand names, Esomperazole Analogs

Esomperazole Brand Names Mixture

No information avaliable

Esomperazole Chemical_Formula

C₁₇H₁₉N₃O₃S

Esomperazole RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Esomperazole fda sheet

Esomperazole FDA

Esomperazole msds (material safety sheet)

Esomperazole Synthesis Reference

No information avaliable

Esomperazole Molecular Weight

345.417 g/mol

Esomperazole Melting Point

155 ^oC

Esomperazole H₂O Solubility

Very slightly soluble in water

Esomperazole State

Solid

Esomperazole LogP

1.078

Esomperazole Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Esomperazole Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Esomperazole Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Esomperazole Absorption

90%

Esomperazole side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Esomperazole Patient Information