Nexiam

Nexiam Brand names, Nexiam Analogs

Nexiam Brand Names Mixture

No information avaliable

Nexiam Chemical_Formula

C₁₇H₁₉N₃O₃S

Nexiam RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Nexiam fda sheet

Nexiam FDA

Nexiam msds (material safety sheet)

Nexiam Synthesis Reference

No information avaliable

Nexiam Molecular Weight

345.417 g/mol

Nexiam Melting Point

155 ^oC

Nexiam H₂O Solubility

Very slightly soluble in water

Nexiam State

Solid

Nexiam LogP

1.078

Nexiam Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Nexiam Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Nexiam Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Nexiam Absorption

90%

Nexiam side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Nexiam Patient Information