Zegerid

Zegerid Brand names, Zegerid Analogs

Zegerid Brand Names Mixture

No information avaliable

Zegerid Chemical_Formula

C₁₇H₁₉N₃O₃S

Zegerid RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Zegerid fda sheet

Zegerid FDA

Zegerid msds (material safety sheet)

Zegerid Synthesis Reference

No information avaliable

Zegerid Molecular Weight

345.417 g/mol

Zegerid Melting Point

155 ^oC

Zegerid H₂O Solubility

Very slightly soluble in water

Zegerid State

Solid

Zegerid LogP

1.078

Zegerid Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Zegerid Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Zegerid Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Zegerid Absorption

90%

Zegerid side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Zegerid Patient Information