Esomeprazole and Salts

Esomeprazole and Salts Brand names, Esomeprazole and Salts Analogs

Esomeprazole and Salts Brand Names Mixture

No information avaliable

Esomeprazole and Salts Chemical_Formula

C₁₇H₁₉N₃O₃S

Esomeprazole and Salts RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Esomeprazole and Salts fda sheet

Esomeprazole_and_Salts FDA

Esomeprazole and Salts msds (material safety sheet)

Esomeprazole and Salts Synthesis Reference

No information avaliable

Esomeprazole and Salts Molecular Weight

345.417 g/mol

Esomeprazole and Salts Melting Point

155 ^oC

Esomeprazole and Salts H₂O Solubility

Very slightly soluble in water

Esomeprazole and Salts State

Solid

Esomeprazole and Salts LogP

1.078

Esomeprazole and Salts Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Esomeprazole and Salts Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Esomeprazole and Salts Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Esomeprazole and Salts Absorption

90%

Esomeprazole and Salts side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Esomeprazole and Salts Patient Information