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Preveon Brand names, Preveon Analogs

Preveon Brand Names Mixture

  • No information avaliable

Preveon Chemical_Formula


Preveon RX_link

Preveon fda sheet

Preveon FDA

Preveon msds (material safety sheet)

Preveon MSDS

Preveon Synthesis Reference

No information avaliable

Preveon Molecular Weight

501.471 g/mol

Preveon Melting Point

No information avaliable

Preveon H2O Solubility

19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2.

Preveon State


Preveon LogP


Preveon Dosage Forms

Tablet (10 mg)

Preveon Indication

For the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Preveon Pharmacology

Adefovir dipivoxil a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV). The concentration of adefovir that inhibited 50% of viral DNA synthesis (IC50) in vitro ranged from 0.2 to 2.5 μM in HBV transfected human hepatoma cell lines. The combination of adefovir with lamivudine showed additive anti-HBV activity.

Preveon Absorption

Approximate oral bioavailability is 59%.

Preveon side effects and Toxicity

Renal tubular nephropathy characterized by histological alterations and/or increases in BUN and serum creatinine was the primary dose-limiting toxicity associated with administration of adefovir dipivoxil in animals. Nephrotoxicity was observed in animals at systemic exposures approximately 3–10 times higher than those in humans at the recommended therapeutic dose of 10 mg/day.

Preveon Patient Information

Preveon Organisms Affected

Hepatitis B virus