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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C25H31F3O5S
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RX_link
http://www.rxlist.com/cgi/generic2/cutivate.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
G. H. Phillipps, et. Al., U.S. Pat. 4,335,121 (1982)
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Molecular Weight
500.572 g/mol
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Melting Point
272-273 oC
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H2O Solubility
0.51 mg/L (insoluble)
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State
Solid
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LogP
4.068
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Dosage Forms
Metered-dose (aerosol)
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Indication
For the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma.
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Pharmacology
Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma.
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Absorption
The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals