Pindolol en es it fr

Pindolol Brand names, Pindolol Analogs

Pindolol Brand Names Mixture

  • Viskazide 10/25tab (Hydrochlorothiazide + Pindolol)
  • Viskazide 10/50tab (Hydrochlorothiazide + Pindolol)

Pindolol Chemical_Formula

C14H20N2O2

Pindolol RX_link

http://www.rxlist.com/cgi/generic3/pindolol.htm

Pindolol fda sheet

Pindolol msds (material safety sheet)

Pindolol MSDS

Pindolol Synthesis Reference

No information avaliable

Pindolol Molecular Weight

248.321 g/mol

Pindolol Melting Point

167-171 oC

Pindolol H2O Solubility

7880 mg/L

Pindolol State

Solid

Pindolol LogP

2.525

Pindolol Dosage Forms

Tablet

Pindolol Indication

For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.

Pindolol Pharmacology

Pindolol is a non-selective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in therapeutic dosage ranges but does not possess quinidine-like membrane stabilizing activity. Pindolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Pindolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Pindolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, pindolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.

Pindolol Absorption

Rapidly and reproducibly absorbed (bioavailability greater than 95%).

Pindolol side effects and Toxicity

LD50=263 mg/kg (orally in rats). Signs of overdose include excessive bradycardia, cardiac failure, hypotension, and bronchospasm.

Pindolol Patient Information

Pindolol Organisms Affected

Humans and other mammals