Blockin L
Blockin L Brand names, Blockin L Analogs
Blockin L Brand Names Mixture
- Viskazide 10/25tab (Hydrochlorothiazide + Pindolol)
- Viskazide 10/50tab (Hydrochlorothiazide + Pindolol)
Blockin L Chemical_Formula
C14H20N2O2
Blockin L RX_link
http://www.rxlist.com/cgi/generic3/pindolol.htm
Blockin L fda sheet
Blockin L msds (material safety sheet)
Blockin L Synthesis Reference
No information avaliable
Blockin L Molecular Weight
248.321 g/mol
Blockin L Melting Point
167-171 oC
Blockin L H2O Solubility
7880 mg/L
Blockin L State
Solid
Blockin L LogP
2.525
Blockin L Dosage Forms
Tablet
Blockin L Indication
For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Blockin L Pharmacology
Pindolol is a non-selective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in therapeutic dosage ranges but does not possess quinidine-like membrane stabilizing activity. Pindolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Pindolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Pindolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, pindolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Blockin L Absorption
Rapidly and reproducibly absorbed (bioavailability greater than 95%).
Blockin L side effects and Toxicity
LD50=263 mg/kg (orally in rats). Signs of overdose include excessive bradycardia, cardiac failure, hypotension, and bronchospasm.
Blockin L Patient Information
Blockin L Organisms Affected
Humans and other mammals
