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Pynastin Brand names, Pynastin Analogs

Pynastin Brand Names Mixture

  • Viskazide 10/25tab (Hydrochlorothiazide + Pindolol)
  • Viskazide 10/50tab (Hydrochlorothiazide + Pindolol)

Pynastin Chemical_Formula


Pynastin RX_link

Pynastin fda sheet

Pynastin msds (material safety sheet)

Pynastin MSDS

Pynastin Synthesis Reference

No information avaliable

Pynastin Molecular Weight

248.321 g/mol

Pynastin Melting Point

167-171 oC

Pynastin H2O Solubility

7880 mg/L

Pynastin State


Pynastin LogP


Pynastin Dosage Forms


Pynastin Indication

For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.

Pynastin Pharmacology

Pindolol is a non-selective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in therapeutic dosage ranges but does not possess quinidine-like membrane stabilizing activity. Pindolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Pindolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Pindolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, pindolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.

Pynastin Absorption

Rapidly and reproducibly absorbed (bioavailability greater than 95%).

Pynastin side effects and Toxicity

LD50=263 mg/kg (orally in rats). Signs of overdose include excessive bradycardia, cardiac failure, hypotension, and bronchospasm.

Pynastin Patient Information

Pynastin Organisms Affected

Humans and other mammals