Phenylacetamidopenicillanic Acid
Phenylacetamidopenicillanic Acid Brand names, Phenylacetamidopenicillanic Acid Analogs
- Abbocillin
- Ayercillin
- Benzopenicillin
- Benzylpenicillin
- Benzylpenicillin G
- Benzylpenicillinic Acid
- Bicillin
- Bicillin L-A
- Cillora
- Cilloral
- Cilopen
- Compocillin G
- Cosmopen
- Crysticillin 300 A.S.
- Dropcillin
- Duracillin A.S.
- Free Benzylpenicillin
- Free Penicillin G
- Free Penicillin Ii
- Galofak
- Gelacillin
- Liquacillin
- Megacillin
- Pencillin G
- Penicillin
- Penicillin G Potassium
- Penicillin G Potassium in Plastic Container
- Penicillin G Procaine
- Penicillin G Sodium
- Penicillin-G Potassium
- Penicillinic Acid, Benzyl-
- Pentids
- Pentids '200'
- Permapen
- Pfizerpen
- Pfizerpen G
- Pfizerpen-As
- Pharmacillin
- Phenylacetamidopenicillanic Acid
- Pradupen
- Specilline G
- Ursopen
- Wycillin
Phenylacetamidopenicillanic Acid Brand Names Mixture
- No information avaliable
Phenylacetamidopenicillanic Acid Chemical_Formula
C16H18N2O4S
Phenylacetamidopenicillanic Acid RX_link
http://www.rxlist.com/cgi/generic3/pengk.htm
Phenylacetamidopenicillanic Acid fda sheet
Phenylacetamidopenicillanic Acid msds (material safety sheet)
Phenylacetamidopenicillanic Acid Synthesis Reference
No information avaliable
Phenylacetamidopenicillanic Acid Molecular Weight
334.391 g/mol
Phenylacetamidopenicillanic Acid Melting Point
214-217oC
Phenylacetamidopenicillanic Acid H2O Solubility
Slightly soluble (210 mg/L)
Phenylacetamidopenicillanic Acid State
Solid
Phenylacetamidopenicillanic Acid LogP
1.212
Phenylacetamidopenicillanic Acid Dosage Forms
Powder for solution; Suspension; Tablet
Phenylacetamidopenicillanic Acid Indication
For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.
Phenylacetamidopenicillanic Acid Pharmacology
Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Phenylacetamidopenicillanic Acid Absorption
Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.
Phenylacetamidopenicillanic Acid side effects and Toxicity
Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.
Phenylacetamidopenicillanic Acid Patient Information
No information avaliable
Phenylacetamidopenicillanic Acid Organisms Affected
Enteric bacteria and other eubacteria
