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Megacillin Brand names, Megacillin Analogs

Megacillin Brand Names Mixture

  • No information avaliable

Megacillin Chemical_Formula


Megacillin RX_link

Megacillin fda sheet

Megacillin msds (material safety sheet)

Megacillin MSDS

Megacillin Synthesis Reference

No information avaliable

Megacillin Molecular Weight

334.391 g/mol

Megacillin Melting Point


Megacillin H2O Solubility

Slightly soluble (210 mg/L)

Megacillin State


Megacillin LogP


Megacillin Dosage Forms

Powder for solution; Suspension; Tablet

Megacillin Indication

For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.

Megacillin Pharmacology

Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.

Megacillin Absorption

Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.

Megacillin side effects and Toxicity

Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.

Megacillin Patient Information

No information avaliable

Megacillin Organisms Affected

Enteric bacteria and other eubacteria