Crysticillin 300 A.S.
Brand names,
Crysticillin 300 A.S.
Analogs
Crysticillin 300 A.S.
Brand Names Mixture
Crysticillin 300 A.S.
Chemical_Formula
C16H18N2O4S
Crysticillin 300 A.S.
RX_link
http://www.rxlist.com/cgi/generic3/pengk.htm
Crysticillin 300 A.S.
fda sheet
Crysticillin 300 A.S.
msds (material safety sheet)
Crysticillin 300 A.S.
Synthesis Reference
No information avaliable
Crysticillin 300 A.S.
Molecular Weight
334.391 g/mol
Crysticillin 300 A.S.
Melting Point
214-217oC
Crysticillin 300 A.S.
H2O Solubility
Slightly soluble (210 mg/L)
Crysticillin 300 A.S.
State
Solid
Crysticillin 300 A.S.
LogP
1.212
Crysticillin 300 A.S.
Dosage Forms
Powder for solution; Suspension; Tablet
Crysticillin 300 A.S.
Indication
For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.
Crysticillin 300 A.S.
Pharmacology
Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Crysticillin 300 A.S.
Absorption
Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.
Crysticillin 300 A.S.
side effects and Toxicity
Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.
Crysticillin 300 A.S.
Patient Information
No information avaliable
Crysticillin 300 A.S.
Organisms Affected
Enteric bacteria and other eubacteria