Benzylpenicillin G
Benzylpenicillin G Brand names, Benzylpenicillin G Analogs
- Abbocillin
- Ayercillin
- Benzopenicillin
- Benzylpenicillin
- Benzylpenicillin G
- Benzylpenicillinic Acid
- Bicillin
- Bicillin L-A
- Cillora
- Cilloral
- Cilopen
- Compocillin G
- Cosmopen
- Crysticillin 300 A.S.
- Dropcillin
- Duracillin A.S.
- Free Benzylpenicillin
- Free Penicillin G
- Free Penicillin Ii
- Galofak
- Gelacillin
- Liquacillin
- Megacillin
- Pencillin G
- Penicillin
- Penicillin G Potassium
- Penicillin G Potassium in Plastic Container
- Penicillin G Procaine
- Penicillin G Sodium
- Penicillin-G Potassium
- Penicillinic Acid, Benzyl-
- Pentids
- Pentids '200'
- Permapen
- Pfizerpen
- Pfizerpen G
- Pfizerpen-As
- Pharmacillin
- Phenylacetamidopenicillanic Acid
- Pradupen
- Specilline G
- Ursopen
- Wycillin
Benzylpenicillin G Brand Names Mixture
- No information avaliable
Benzylpenicillin G Chemical_Formula
C16H18N2O4S
Benzylpenicillin G RX_link
http://www.rxlist.com/cgi/generic3/pengk.htm
Benzylpenicillin G fda sheet
Benzylpenicillin G msds (material safety sheet)
Benzylpenicillin G Synthesis Reference
No information avaliable
Benzylpenicillin G Molecular Weight
334.391 g/mol
Benzylpenicillin G Melting Point
214-217oC
Benzylpenicillin G H2O Solubility
Slightly soluble (210 mg/L)
Benzylpenicillin G State
Solid
Benzylpenicillin G LogP
1.212
Benzylpenicillin G Dosage Forms
Powder for solution; Suspension; Tablet
Benzylpenicillin G Indication
For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.
Benzylpenicillin G Pharmacology
Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Benzylpenicillin G Absorption
Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.
Benzylpenicillin G side effects and Toxicity
Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.
Benzylpenicillin G Patient Information
No information avaliable
Benzylpenicillin G Organisms Affected
Enteric bacteria and other eubacteria
