PharmacyCodes



Phentolamine en es it fr

Phentolamine Brand names, Phentolamine Analogs

Phentolamine Brand Names Mixture

  • No information avaliable

Phentolamine Chemical_Formula

C17H19N3O

Phentolamine RX_link

http://www.rxlist.com/cgi/generic3/phentol.htm

Phentolamine fda sheet

Phentolamine msds (material safety sheet)

Phentolamine Synthesis Reference

No information avaliable

Phentolamine Molecular Weight

281.352 g/mol

Phentolamine Melting Point

174.5 oC

Phentolamine H2O Solubility

No information avaliable

Phentolamine State

Solid

Phentolamine LogP

2.551

Phentolamine Dosage Forms

Liquid

Phentolamine Indication

For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.

Phentolamine Pharmacology

Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.

Phentolamine Absorption

No information avaliable

Phentolamine side effects and Toxicity

No information avaliable

Phentolamine Patient Information

No information avaliable

Phentolamine Organisms Affected

Humans and other mammals